HDExaminer in the Literature
Below is a selected list of publications assisted by HDExaminer. For a more complete listing, visit Google Scholar.
Jukyung Kang, Sang Yeop Kim, Daniel Vallejo, Tyler S. Hageman, Derek R. White, Alexander Benet, Jill Coghlan, K. Ilker Sen, Michael Ford, Sergei Saveliev, Thomas J. Tolbert, David D. Weis, Steven P. Schwendeman, Brandon T. Ruotolo, and Anna Schwendeman. Multifaceted assessment of rituximab biosimilarity: The impact of glycan microheterogeneity on Fc function. European Journal of Pharmaceutics and Biopharmaceutics (2020).
Awital Bar Barroeta, Josse van Galen, Ingrid Stroo, J. Arnoud Marquart, Alexander B. Meijer, and Joost C. M. Meijers. Hydrogen‐deuterium exchange mass spectrometry highlights conformational changes induced by factor XI activation and binding of factor IX to factor XIa. Journal of Thrombosis and Haemostasis (2019).
Kammari, Rajashekar, and Elizabeth M. Topp. Solid-state Hydrogen Deuterium Exchange Mass Spectrometry (ssHDX-MS) of Lyophilized Poly-D, L-alanine. Molecular Pharmaceutics (2019).
Hageman, Tyler S., and David D. Weis. Reliable identification of significant differences in differential HX-MS measurements using a hybrid significance testing approach. Analytical Chemistry (2019).
Soya, N., Roldan, A., & Lukacs, G. L. Differential Scanning Fluorimetry and Hydrogen Deuterium Exchange Mass Spectrometry to Monitor the Conformational Dynamics of NBD1 in Cystic Fibrosis. In Protein Misfolding Diseases. Humana Press, New York, NY, (2019): 53-67.
Ravenhill, Benjamin J., Keith B. Boyle, Natalia von Muhlinen, Cara J. Ellison, Glenn R. Masson, Elsje G. Otten, Agnes Foeglein, Roger Williams, and Felix Randow. The Cargo Receptor NDP52 Initiates Selective Autophagy by Recruiting the ULK Complex to Cytosol-Invading Bacteria. Molecular cell (2019).
Coufalova, Dominika, Lucy Remnant, Lenka Hernychova, Petr Muller, Alan Healy, Srinivasaraghavan Kannan, Nicholas Westwood et al. An inter-subunit protein-peptide interface that stabilizes the specific activity and oligomerization of the AAA+ chaperone Reptin. Journal of proteomics 199 (2019): 89-101.
Karch, Kelly R., Mariel Coradin, Levani Zandarashvili, Zhong-Yuan Kan, Morgan Gerace, S. Walter Englander, Ben E. Black, and Benjamin A. Garcia. Hydrogen-deuterium exchange coupled to top-and middle-down mass spectrometry enables high-resolution measurements of histone tail dynamics before and after nucleosome assembly. bioRxiv (2018): 310177.
Berry, Luke, Angela Patterson, Natasha Pence, John W. Peters, and Brian Bothner. Hydrogen Deuterium Exchange Mass Spectrometry of Oxygen Sensitive Proteins, Bio-protocol 8, no. 6 (2018).
Wang, Andrea L., Ying Zhou, Michael J. Palmieri, and Gang G. Hao. Hydrogen deuterium exchange reveals changes to protein dynamics of recombinant human erythropoietin upon N-and O-desialylation. Journal of pharmaceutical and biomedical analysis 154 (2018): 454-459.
Lo, Yi-Ting, Huang, Hung-Wei, Huang, Yi-Chuan, Chan, Jui-Fen, Hsu, Yuan-Hao Howard. Elucidation of tRNA–cytochrome c interactions through hydrogen/deuterium exchange mass spectrometry, Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1865.5 (2017): 539-546.
Forest, Eric, and Petr Man. Conformational dynamics and interactions of membrane proteins by hydrogen/deuterium mass spectrometry, Heterologous Expression of Membrane Proteins. Humana Press, New York, NY, (2016): 269-279.
Brooun, Alexei, Ketan S. Gajiwala, Ya-Li Deng, Wei Liu, Ben Bolanos, Patrick Bingham, You-Ai He et al. Polycomb repressive complex 2 structure with inhibitor reveals a mechanism of activation and drug resistance. Nature communications 7 (2016): 11384.
Prądzińska, Martyna, Izabela Behrendt, Juan Astorga-Wells, Aleksandr Manoilov, Roman A. Zubarev, Aleksandra S. Kołodziejczyk, Sylwia Rodziewicz-Motowidło, and Paulina Czaplewska. Application of amide hydrogen/deuterium exchange mass spectrometry for epitope mapping in human cystatin C. Amino acids 48, no. 12 (2016): 2809-2820.
Yang, Sheng-Wei, Hsiu-Chi Ting, Yi-Ting Lo, Ting-Yuan Wu, Hung-Wei Huang, Chia-Jung Yang, Jui-Fen Riva Chan, Min-Chieh Chuang, and Yuan-Hao Howard Hsu. Guanine nucleotide induced conformational change of Cdc42 revealed by hydrogen/deuterium exchange mass spectrometry. Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1864, no. 1 (2016): 42-51.
Clarke, Jonathan H., Maria-Luisa Giudici, John E. Burke, Roger L. Williams, David J. Maloney, Juan Marugan, and Robin F. Irvine. The function of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) explored using a specific inhibitor that targets the PI5P-binding site. Biochemical Journal 466, no. 2 (2015): 359-367.
Keppel, Theodore R., and David D. Weis. Mapping residual structure in intrinsically disordered proteins at residue resolution using millisecond hydrogen/deuterium exchange and residue averaging. Journal of the American society for mass spectrometry 26, no. 4 (2015): 547-554.
Venable, J.D., Scuba, W. & Brock, A. Feature Based Retention Time Alignment for Improved HDX MS Analysis, J. Am. Soc. Mass Spectrom. (2013) 24: 642.
Burke, John E., and Roger L. Williams. Dynamic steps in receptor tyrosine kinase mediated activation of class IA phosphoinositide 3-kinases (PI3K) captured by H/D exchange (HDX-MS). Advances in biological regulation 53, no. 1 (2013): 97-110.
Venable, J. D., Okach, L., Agarwalla, S., & Brock, A. Subzero temperature chromatography for reduced back-exchange and improved dynamic range in amide hydrogen/deuterium exchange mass spectrometry. Analytical chemistry, 84(21), (2012): 9601-9608.